New approaches for the development of antibiotics and cancer treatment, reusing more beverage packaging and the key factor for the beginning of life: awards for young researchers

Five young scientists were honoured for their internationally outstanding work in Salzburg during the opening of the 15th ÖGMBT Annual Meeting: The Life Science Research Awards Austria 2023 of the Austrian Society for Molecular Biosciences and Biotechnology (ÖGMBT) went to Johanna Gassler (formerly IMBA), David Hoi (IMP) and Klemens Kremser (BOKU). The prizes of 3,000 euros each were awarded with the support of the Austrian Federal Ministry of Labour and Economy. Alexander Hanzl (CeMM) and Matthias Hinterndorfer (IMP) received the Life Science PhD Award Austria for their dissertations.

Caption: (from left to right) Rainer Englisch (THP Medical Products, Brigitta Vcelar (Polymun Scientific), Viktoria Weber (president),  Matthias Hinterndorfer, Alexander Hanzl, Johanna Gassler, Klemens Kremser, David Hoi and Ulrike Unterer (BMAW).

 

 

In the category Basic Research, the Life Science Research Award Austria 2023 went to Johanna Gassler for a paper she published during her time at the Institute of Molecular Biotechnology IMBA in Vienna.

The key factor for the first steps of life in the fertilised egg cell

 

In her paper published in Science, Gassler focuses on the first steps of life in a fertilised egg cell (zygote). During the first stages of development, the activation of the zygotic genome is crucial for the development of the organism. Gassler was able to show that the protein Nr5a2 plays a crucial role as a pioneer factor. This mechanism could play a role in all vertebrates. Her findings thus contribute to a better understanding of this early phase of life.

 

Zygotic genome activation by the totipotency pioneer factor Nr5a2

 

The three Life Science Research Awards were once again supported by the Federal Ministry of Labour and Economy. Minister for Labour and Economic Affairs (BMAW) Martin Kocher: "Research and development are key factors for Austria's international competitiveness. They secure high-quality jobs. The Life Science Research Awards Austria promote young scientists - an initiative we are happy to support." Ulrike Unterer from the BMAW spared no effort and traveled to Salzburg to personally congratulate the winners and hand over the prizes.

 

Innovative approach to developing of new antibiotics

 

In the category Applied Research, the Life Science Research Award Austria 2023 went to David Hoi for his work at the Research Institute of Molecular Pathology (IMP) in Vienna. The results of his study represent a highly innovative approach to the development of new antibiotics: Protein degradation molecules such as BacPROTACs, which specifically target bacterial proteins, are being considered as a new class of antibiotics.

David Hoi and his colleagues have shown that BacPROTACs can be successfully used to target and kill tuberculosis pathogens. This suggests that the BacPROTAC platform may also be suitable for the development of new drugs to treat other serious infectious diseases. The study has been published in the leading journal Cell.

Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival

 

Recycling of beverage packaging without the use of aggressive chemicals

 

The special award in the category Excellence and Societal Impact, which will be awarded for the fifth time in 2023, went to Klemens Kremser from the University of Natural Resources and Applied Life Sciences, Vienna. His work describes a novel, environmentally friendly process for recycling the various components of beverage packaging without the use of harsh chemicals: cellulose fibres are removed by enzymes and aluminium is microbially dissolved. The result is pure polyethylene that can be reused as packaging material.

The process developed by Klemens Kremser and his colleagues could significantly increase the reuse of packaging materials in the future. His work has been published in the prestigious journal Resources, Conservation and Recycling.

 

Bioleaching/enzyme-based recycling of aluminium and polyethylene from beverage cartons packaging waste

 

Dissertation prize: The body's own mechanisms against disease-causing proteins

 

In his dissertation, Alexander Hanzl also investigated the field of targeted protein degradation as a therapeutic option. In this process, pathogenic proteins are reduced by the body's own cell mechanisms. This is done using so-called small molecule degraders (E3 ligases). An important aspect of the work was to investigate how resistance to therapy develops. This approach is currently being clinically tested in cancer, neurodegenerative and autoimmune diseases.

Improved targeted therapies also have significant environmental benefits, reducing the need for broad-spectrum drugs.

 

This work has significant application potential. The underlying idea has been patented and has already contributed to the creation of a successful biotech start-up.

 

Identifying novel degraders and resistance mechanisms in targeted protein degradation

 

Dissertation prize for novel use of gene scissors in cancer

 

The Life Science PhD Award Austria 2023 for the most innovative doctoral thesis with high application potential went to Matthias Hinterndorfer from the Research Institute of Molecular Pathology (IMP) in Vienna.

Important cellular building blocks that play a central role in the development of cancer and other diseases are difficult to study. They are often vital for cell survival. It is therefore very difficult for researchers to modify these building blocks. Hinterndorfer made the breakthrough with the remote-controlled use of the gene scissors CRISPR/Cas. This tool can be used to inactivate any human gene and thus prevent the production of the corresponding cell building block. As a result, short-lived building blocks would quickly disappear after the scissors damaged the responsible gene in the cell.

 

Using a chemical substance, Hinterndorfer succeeded in switching on the gene scissors at any time. In this way, a cellular reaction can be triggered before the important elements of the reaction are inactivated by the gene scissors.This discovery opens up new therapeutic approaches for the treatment of cancer.

 

Title of the thesis: Time-resolved genetic screens to dissect gene functions and regulatory networks.

 

The winners were also celebrated in public. Here is a report in the Kronenzeitung

15 years of ÖGMBT: Annual conference is the most important life science event in Austria

 

The ÖGMBT represents 1,300 people and students working in the life sciences as well as 70 companies and institutions. ÖGMBT President Univ.-Prof. Dr. Viktoria Weber at the 15th annual meeting, which this time took place in Salzburg: "The Life Science Awards Austria once again impressively demonstrate the high international standard of Austrian researchers. On behalf of the ÖGMBT, I would like to express my special thanks to our long-standing supporters BMAW, THP Medical Products and Polymun Scientific, who make these awards possible.”

WE ARE VERY PROUD OF OUR WINNERS THIS YEAR AND CONGRATULATE THEM WARMLY!!!!!

Want to know more about the winners  2010-2020? Let have a look at the online FLIP BOOK "SUCCESS STORIES"

Photos: ÖGMBT/dibiasi-momente

 

 

Teilnehmer:innen einer COST Aktion bilden gemeinsam das Action Management Committee (MC). Das MC ist verantwortlich für die Koordination, Implementierung und das Management einer COST Aktion. Pro COST Aktion können bis zu zwei Fachkräfte eines COST Landes als MC Member nominiert werden. Die Nominierung ist auch nach dem Start einer COST Aktion möglich. Interessierte Fachkräfte aus Österreich werden über die FFG nominiert. COST Aktionen, die für eine österreichische Beteiligung offen sind, finden Sie unter „COST Aktionen OFFEN für österreichische Beteiligungen".

 

Vor dem offiziellen Start der Actions (die ersten Actions starten ab 18.09.2023) kann die FFG noch die Nominierung mit sofortiger Wirkung vornehmen. Nach dem Start erfolgt die Nominierung ebenfalls über die FFG, es ist jedoch die Aufnahme durch den Action Chair und das Management Committee notwendig.

Sie möchten sich als Mitglied des Management Committees bewerben? Anträge können über den FFG eCall gestellt werden!

Eine Liste mit freien Positionen in den Action Management Committees findet sich nach Themenbereichen geordnet unter folgenden Links:

Natural Sciences

Engineering&Technology

Medical and Health Sciences

Agricultural Sciences

Social Sciences

Humanities

Kontakt: cost(at)ffg.at

https://www.ffg.at/europa/cost_teilnahmebedingungen

 

Bist du Student:in eines naturwissenschaftlichen Fachbereichs und interessierst dich für das Thema Nahrungsmittelunverträglichkeiten und Allergien? Schreibst du gern? Bist du kreativ? Möchtest du Erfahrung in der Wissenschaftskommunikation sammeln? Treffen einer oder mehrere Punkte auf dich zu, dann bekommst du beim Projekt INDIKINA jetzt die Möglichkeit, beim Gestalten eines interaktiven Kinderbuches zum Thema Allergien mitzuwirken. 

Das Projekt

Im Rahmen des Projekts INDIKINA (INteraktives, DIgitales KInderbuch zum Thema NAhrungsmittelallergien) soll ein interaktives, digitales Kinderbuch für 8- bis 10-Jährige entstehen. Dieses Buch wird auf unterhaltsame Art und Weise grundlegendes Wissen zu Allergien und Nahrungsmittelunverträglichkeiten vermitteln.

Das Besondere und Spannende daran: Das Kinderbuch wird gemeinsam mit der Zielgruppe, nämlich 8- bis 10-jährigen Volksschulkindern, erarbeitet. Von der Konzeption bis zur Umsetzung sind diese in die Entstehung des Kinderbuchs mit eingebunden. Der Input und das Feedback der Schüler:innen werden dazu beitragen, das Buch optimal an die Kenntnisse, Interessen und Bedürfnisse der Altersgruppe anzupassen.

INDIKINA wird von Ines Swoboda (FH Campus Wien, Leiterin des Kompetenzzentrums für Molecular Biotechnology) geleitet, zum Projektteam zählen außerdem Open Science, das Institut für Jugendliteratur und das Softwareunternehmen Vienom. Gefördert wird das Projekt durch den FWF.

Student:innen für die Mitgestaltung gesucht!

Bei der Gestaltung des Kinderbuches sollen auch Studierende aus dem Gesundheits- oder Life-Sciences-Bereich das Projektteam ­mit ihrem Know-How und ihrer Kreativität unterstützen. Die Studierenden können entweder beim Erstellen der Geschichte oder bei deren grafischer Umsetzung mitwirken. Dafür werden sie zuvor in Workshops durch das Institut für Jugendliteratur oder das Softwareunternehmen Vienom gecoacht. INDIKINA bietet Student:innen somit die einzigartige Möglichkeit, hier wertvolle Erfahrung für einen möglichen späteren Berufsweg zu sammeln. Jede/r Mitwirkende wird des Weiteren namentlich im Kinderbuch genannt.

Zeitplan und Arbeitsumfang

Im September 2023 wird ein erstes Treffen aller Interessent:innen an der FH Campus Wien stattfinden, bei dem auch die Einteilung in zwei Gruppen erfolgt: Entweder ist die Mitarbeit beim Erstellen der Geschichte oder bei deren grafischer Gestaltung möglich.

In zwei bis drei Workshops, deren Zeitpunkt und Dauer noch in Abstimmung mit den Studierenden festgelegt wird, erfolgt vor Weihnachten dann das Coaching und das Erstellen des Kinderbuchkonzepts.    

Ab Jänner 2024 wird das von den Studierenden konzipierte Kinderbuch von Vienom programmiert und vom Illustrator/ der Illustratorin illustriert. Nach der Einarbeitung von Feedback der Schüler:innen wird das interaktive Kinderbuch anschließend über die Kanäle aller am Projekt beteiligten verbreitet und auch bei einer öffentlichen Buchpräsentation vorgestellt.

 

Interessent:innen können sich melden bei: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

FEMS is inviting applications to three positions on the Board – President, Secretary General and Director of Business and Policy for the term from January 1, 2024 to December 31, 2026.

For job descriptions and details please refer to https://fems-microbiology.org/inviting-applications-to-three-positions-on-our-board/  Application deadline is April 30, 2023.

Interested ÖGMBT members, please contact This email address is being protected from spambots. You need JavaScript enabled to view it.

The ÖGMBT is a member of several relevant scientific societies (FEBS, FEMS and EFB) and our members are automatically members of these societies and can take advantage of benefits such as travel grants, short-term and long-term fellowships and much more. See also: https://fems-microbiology.org/

 

 

 

 

Reminder: 47th FEBS Congress (‘FEBS 2023’), July 8 – 12, 2023, Tours/France. Attracting up to 2.000 attendees, the Congress provides a platform for international scientific exchange and showcases the newest developments in biochemistry, molecular biology and related areas.

FEBS Young Scientists’ Forum (YSF), July 6 - 8, 2023. A lively gathering of over 100 PhD students and young postdocs, whose attendance at this event and the ensuing FEBS Congress is funded by FEBS YSF grants.

 

The ÖGMBT is a member of several relevant scientific societies (FEBS, FEMS and EFB) and our members are automatically members of these societies and can take advantage of benefits such as travel grants, short-term and long-term fellowships and much more. See also: https://www.febs.org/other-activities/science-society/

 

 

Mit der Exzellenzinitiative excellent=austria schlägt Österreich ein neues Kapitel in der Grundlagenforschung auf: Fünf Exzellenzcluster werden ab Sommer 2023 an elf Standorten kooperative Projekte in noch nie dagewesener Dimension starten. Seitens des FWF sowie der beteiligten Forschungsstätten steht ein Investitionsvolumen von 135 Millionen Euro zur Verfügung, um Spitzenforschung zu Zukunftsthemen für die ersten fünf Jahre der geplanten zehnjährigen Laufzeit zu finanzieren. Wissenschaftsminister Martin Polaschek und FWF-Präsident Christof Gattringer gaben in Wien die lang erwarteten Förderentscheidungen bekannt.

 

AUCH EIN LIFE SCIENCES CLUSTER IST VERTRETEN:

Exzellenzcluster „Microbiomes Drive Planetary Health“
Die Bedeutung von Mikrobiomen für die planetare Gesundheit verstehen

 

Board of Directors und beteiligte Forschungsstätten:

  • Michael Wagner (Director of Research, Universität Wien)
  • Andreas Bergthaler (Österreichische Akademie der Wissenschaften, CeMM)
  • Christina Kaiser (Universität Wien)
  • Bernhard Lendl (Technische Universität Wien)
  • Christine Moissl-Eichinger (Medizinische Universität Graz)
  • Alexander Moschen (Universität Linz)
  • Leonid Sazanov (Institute of Science and Technology Austria)
  • Angela Sessitsch (Austrian Institute of Technology)

FWF-Fördervolumen: 21 Millionen Euro

Mikrobiome – Gemeinschaften von Mikroorganismen, die alle Ökosysteme und Lebewesen besiedeln – sind für die Gesundheit unseres Planeten und seiner Bewohner von wesentlicher Bedeutung. In diesem Exzellenzcluster arbeiten 30 Wissenschaftler:innen verschiedener Fachgebiete aus sieben verschiedenen Forschungsstätten daran, gemeinsame Grundprinzipien von Umwelt-Mikrobiomen und Mikrobiomen des Menschen zu entschlüsseln. Ziel ist es zu ergründen, wie Mikrobiome die Gesundheit unseres Planeten steuern. Mit diesem Wissen wird der globale Wandel besser vorhersagbar und gleichzeitig die gezielte Beeinflussung von Mikrobiomen als innovative Lösung für eine nachhaltige Zukunft ermöglicht. 

„In unserem Exzellenzcluster schaffen wir völlig neue Synergien, indem wir die Grenzen zwischen roter und grüner Mikrobiomforschung in Österreich auflösen und somit direkt Medizin mit Umweltforschung verknüpfen. Wir wollen die Grundprinzipien von Mikrobiomen verstehen lernen, um dann durch deren Modellierung und gezielte Beeinflussung die planetare Gesundheit stärken“, so Michael Wagner, Director of Research des Exzellenzclusters.

GRATULATION!

Weitere Info und Quelle: https://www.fwf.ac.at/de/news-presse/news/nachricht/nid/20230313-0

Interaktive Landkarte: Lernen Sie Österreichs Clusters of Excellence kennen: excellentaustria.fwf.ac.at

 

The LIFE SCIENCE CAREER FAIR (LSCF2023) opens its doors on May 16, 2023, in Vienna (FH Campus Wien, Favoritenstr. 226).

As a platform for job-seekers and potential employers to meet, the LIFE SCIENCE CAREER FAIR will attract students, graduates and young professionals from Austria and abroad, the registration being free of charge for job seekers. Besides the traditional employer exhibition with booths, the career fair will offer an engaging on-site program. Employer pitches and presentations allow you, the exhibiting companies and research institutions to individually present yourself as attractive employers.

The Austrian Association of Molecular Life Sciences and Biotechnology (ÖGMBT) together with their partners Austrian Centre for Industrial Biotechnology (ACIB), FH Campus Wien & Chemiereport are dedicated to showcase the diverse career opportunities in academic and industrial life sciences and beyond. Here a review to the last LSCF2022.

To see the career-boosting activities which ÖGMBT / Young Life Scientists Austria (YLSA) are already featuring, please click HERE.

The LIFE SCIENCE CAREER FAIR is the perfect opportunity for companies, research institutions and other organisations recruiting life scientists to:

  • inform about job profiles and career opportunities in your organisation
  • be visible to the life science community at the event and beyond
  • get access to CVs and profiles of participants in our improved online TALENT POOL
  • interact with future employees on multiple levels

WANT TO BE PART OF THE LIFE SCIENCE CAREER FAIR AS EXHIBITOR?

Sponsor & Exhibitor Manual available - please write to This email address is being protected from spambots. You need JavaScript enabled to view it.

 

There will be a Q & A meeting via zoom on March 15, 14:00 for all interested exhibitors. Please write an email to This email address is being protected from spambots. You need JavaScript enabled to view it. to receive the zoom link.

Discounts for academic institutions & ÖGMBT members available!

We invite all companies, research institutions and related organisations to join us for the LIFE SCIENCE CAREER FAIR promising the ideal opportunity for recruiting and employer branding.

 

FREE REGISTRATION FOR PERSONAL MEMBERS

Our first Life Science Tuesday “Lipids and Metabolism” was well attended, the discussions in the breakout rooms were lively, the Short Talks by young talents were on a high standard and we were enthused by the quality and creativity of the Science Flashes. Thanks to all who participated!

We expect no less at our next Life Science Tuesday #2/12 dedicated to “RNA Biology” supported by LexogenOctober 20 from 13:30 – 18:00 hrs, chaired by Brigitte Pertschy & Sebastian Falk.
 

Invited Speaker Marlene Oeffinger (Institut de recherches cliniques de Montréal, CA) will be talking about “Nuclear mRNA metabolism directs specialization of the nuclear pore complex in yeast”, followed by 4 Short talks and 4 Science flashes by young talents. Last but not least, Renée Schroeder will be giving a presentation on the “Historical Perspective on RNA Research".

Please find here the program/abstract booklet for the afternoon and the teaser video.

<iframe width="1213" height="682" src="https://www.youtube.com/embed/mG4bTCWiPRU?list=PLQhTb-GSQ-9Ccb2BZTb8jA02XgyPibC1s" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe>

 

The Annual Meeting is free of charge for all personal ÖGMBT members!

Registration for the Life Science Tuesdays is at any time possible. For abstract submission check the deadlines on our webpage.

Even without registration we invite you to visit:

Come join us for 11 further Life Science Tuesdays – starting at #2 on October 20! Here the list of all Life Science Tuesdays.

 

We look forward to see you there!

 

Harald Pichler, Helmut Bergler, Alexandra Khassidov

Organizing Committee

 

 

 


 

INTERNATIONAL MICROORGANISM DAY

Monday, 14 September 2020 10:34
17 September is International Microorganism Day, an opportunity to promote the diversity and variety of microorganisms and a way to encourage everyone to recognize and celebrate the many ways microscopic organisms are important in human health, culture and, throughout our daily lives. 
 
International Microorganism Day is an annual celebration of microbiology and this year we are making an even greater effort to promote the positive contributions of microorganisms in our daily lives given the negative stories associated with viruses in the news. 
 
This year we have focused our efforts on online activities: 
 
 
 
 
Microorganisms and their activities have widespread, significant, and generally positive effects on the health and well‐being of human beings and the entire surface of the planet and its atmosphere. Microbes, invisible to the human eye, are the hidden power in many everyday activities, serving to ferment foods and treat sewage, to produce fuel, enzymes, and other bioactive compounds and are a vital component of fertile soil. In the human body, microorganisms make up the human microbiota, including the essential gut flora. The pathogens responsible for many infectious diseases are also microbes and as such are the target of disease prevention and control measures. 
 
The scientific study of microorganisms began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. 17 of September was chosen to acknowledge the date in 1683 van Leeuwenhoek - a Dutch merchant with no formal education - sent a letter to the Royal Society in London, reporting the first description of a single-celled organism. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage and Robert Koch in the 1880s discovered that microorganisms caused the diseases tuberculosis, cholera, and anthrax. 
 
Microorganisms include all unicellular organisms and so are extremely diverse. They live in almost every habitat from the poles to the equator, deserts, geysers, rocks, and the deep sea. Some are adapted to extremes such as very hot or very cold conditions, others to high pressure, and a few to high radiation environments. There is evidence that 3.45-billion-year-old Australian rocks once contained microorganisms, the earliest direct evidence of life on Earth. 
 
However, unlike other subjects having a significant impact upon humankind, knowledge of these vital microbial activities, how they impact our lives, and how they may be harnessed for the benefit of humankind – microbiology literacy – is low among the public and decision makers. An understanding of key microbial activities is essential in society for informed personal decisions, as well as for policy development in government and business.  
 
We hope this can be addressed by microbiologists, microbiological learned societies, microbiology‐literate professionals and all microbe lovers around their world sharing their passion and knowledge of microbes and their value to all humankind on 17 September. Microbiologists from across the globe will be contributing to International Microorganism Day, developing appealing teaching materials, introducing research in an engaging way, sharing interesting facts and stories about microorganisms and their impact. We hope to demonstrate to educators, policy makers, business leaders and relevant governmental and non‐governmental agencies the significance of microorganism and the need for education support increased understanding of their importance and significance and through this, microbiology literacy in society will become reality. 
 
About International Microorganism Day
International Microorganism Day is an initiative launched by the Portuguese Society of Microbiology in 2017 to combine science dissemination activities. Since that initial edition, celebrations have been held in Portugal and internationally under a cohesive identity through logos and mascots produced in Portugal. It has been supported by FEMS to increase the size and impact of these events and especially in 2020, to present the positive aspects of microorganisms.  
 
About FEMS
The Federation of European Microbiological Societies (FEMS) is a not-for-profit organization, established in 1974 to advance microbiology for the benefit of society in the areas of health, energy, food, materials, and the environment. We are committed to supporting microbiologists do their work; promoting the best in microbiology research and knowledge to the world and, bringing microbiologists together to share that knowledge. We reinvest our revenues into supporting microbiologists throughout their career, publishing and promoting scientific research in our journals and organizing events to bring scientists together. 
 
Information for Editors
A full media pack including logos, images and the International Microorganism Day mascots is here: https://www.internationalmicroorganismday.org/media-resources
 
Social media hashtags for the event are #InternationalMicroorganismDay #WhyMicroMatters and #MicrobiologyIsEverywhere
 
The story of why 17 September was chosen as IMD and the discovery of microbes by Antonie van Leeuvwenhoek is here: https://fems-microbiology.org/femsmicroblog-17-september-is-international-microorganism-day-but-why-17-september/  
 
All media enquiries should be sent to Joe Shuttleworth (FEMS Science Communications Officer) This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Phoenestra GmbH

Thursday, 06 August 2020 04:01

Phoenestra GmbH

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