BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//jEvents 2.0 for Joomla//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VTIMEZONE
TZID:Europe/Vienna
BEGIN:STANDARD
DTSTART:20211031T020000
RDATE:20220327T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20221030T020000
RDATE:20230326T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20231029T020000
RDATE:20240331T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20241027T020000
RDATE:20250330T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20251026T020000
RDATE:20260329T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20261025T020000
RDATE:20270328T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20271031T020000
RDATE:20280326T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20281029T020000
RDATE:20290325T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20291028T020000
RDATE:20300331T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20301027T020000
RDATE:20310330T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20311026T020000
RDATE:20320328T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20321031T020000
RDATE:20330327T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20331030T020000
RDATE:20340326T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:STANDARD
DTSTART:20341029T020000
RDATE:20350325T030000
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:Europe/Vienna CET
END:STANDARD
BEGIN:DAYLIGHT
DTSTART:20210919T090000
RDATE:20211031T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20220327T030000
RDATE:20221030T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20230326T030000
RDATE:20231029T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20240331T030000
RDATE:20241027T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20250330T030000
RDATE:20251026T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20260329T030000
RDATE:20261025T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20270328T030000
RDATE:20271031T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20280326T030000
RDATE:20281029T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20290325T030000
RDATE:20291028T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20300331T030000
RDATE:20301027T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20310330T030000
RDATE:20311026T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20320328T030000
RDATE:20321031T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20330327T030000
RDATE:20331030T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
BEGIN:DAYLIGHT
DTSTART:20340326T030000
RDATE:20341029T020000
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:Europe/Vienna CEST
END:DAYLIGHT
END:VTIMEZONE
BEGIN:VEVENT
UID:
CATEGORIES:Kongress
SUMMARY:IMB/SFB1361 Conference “Restore, Reorganise, Repurpose: The many faces of DNA repair"
LOCATION:Mainz, Germany
DESCRIPTION;ENCODING=QUOTED-PRINTABLE:			SFB 1361 - Regulation of DNA repair and genome stability	DNA is the carr
 ier of a cell’s genetic information. As such, it needs to be maintain
 ed for long-term storage, duplicated as the cell proliferates, and made acc
 essible for read-out in order to support cellular metabolism. However, like
  all biological molecules, DNA is vulnerable to damage and decay, which nec
 essitates a battery of defensive mechanisms to protect it against a multitu
 de of threats.\n	Over the past decades, the major pathways of genome mainte
 nance and their key players have been elucidated, providing insight into ho
 w various sources of genotoxic stress are detected by the cell and channell
 ed into appropriate maintenance pathways. Yet, the origins of genome instab
 ility are extremely diverse and sometimes unforeseeable as they arise in a 
 changing environment. Moreover, DNA lesions are often interconvertible by t
 he cell’s own metabolism or defence pathways, and their biological ef
 fects depend on factors such as the cell type, the cell cycle stage or thei
 r location within the genome. As a consequence, the cellular response to ge
 notoxic insults exhibits a corresponding flexibility, and a given insult ca
 n usually be processed by more than one particular pathway, with sometimes 
 vastly different outcomes for the cell and the organism.\n	Today’s ma
 jor challenge lies in understanding the regulatory mechanisms that control 
 the choice between the individual pathways in the context of chromatin, the
  cell nucleus and the cell’s physiological state in general, their fi
 delity and their interdependencies in response to different insults.\n	Eluc
 idating the molecular mechanisms that modulate the activities of genome mai
 ntenance pathways in the cell will be the central goal of the SFB 1361. \n\
 n\n	The consortium will approach this goal on three interconnected levels, 
 encompassing\n\n\n	(1) the origins of genome instability,\n	(2) the percept
 ion of genotoxic stress (damage sensing) and\n	(3) the systems for its reso
 lution (DNA repair).\n\n\n\n			 						This interdisciplinary network b
 rings together experts in structural biology, organic chemistry, biochemist
 ry, molecular and cell biology as well as genetic toxicology and clinical s
 ciences from Mainz, Darmstadt, Frankfurt and Munich. It will make use of st
 ate-of-the-art tools in microscopy, proteomics, genomics, damage detection 
 and quantification as well as a wide panel of DNA repair assays.\n					POST
 ER\n	\n\n	 \n
CONTACT:https://www.sfb1361.de/
DTSTAMP:20260630T002349Z
DTSTART;TZID=Europe/Vienna:20220920T090000
DTEND;TZID=Europe/Vienna:20220923T180000
SEQUENCE:1
TRANSP:OPAQUE
END:VEVENT
END:VCALENDAR